• saffron extract powder
  • saffron extract powder

saffron extract powder

Saffron extract, also known as Saffron P.E., is a product extracted from the upper part and stigma of the iris plant Crocus sativus L.. Saffron extract has many ingredients and is a super antioxidant. Saffron extract is also used Various kidney-protecting supplements
Product Name
saffron extract
Specification
0.3%
Appearance
Purple red powder
CAS No
84604-17-1
Packaging
25kg cardboard drum
  • saffron extract powder

Desciption

Product information                                                                                                                                                  
What is Saffron extract powder?
Saffron extract is a product extracted from the upper part and stigma of the iris plant Crocus sativus L.. The main ingredients include picrocrocin, carotene compounds, safflower aldehyde, eucalyptol, pinene and other substances. Contains a small amount of isorhamnetin, kaempferol, vitamin B1 and vitamin B2. Saffron extract is a powerful scavenger of hydroxyl free radicals and superoxide free radicals. It can resist oxidation reactions, improve mitochondrial function, inhibit optic nerve cell apoptosis, improve microcirculation, improve immunity, resist arteriosclerosis, and resist oxidation. It has the functions of lowering blood lipids, promoting choleretics and liver protection, preventing and treating osteoporosis, and protecting kidneys.
Joyous Saffron extract powder specification
Terms Standard Terms Standard
Product Name Saffron extract

Appearance

Purple red powder

Assay 0.3%

Loss on Drying

≤2%

Total Heavy Metals

≤10 ppm

Ash

≤2%

As

≤0.5ppm

Total Plate Count

≤750 cfu/g

Pb

≤0.5ppm

Yeast and Mold

≤100 cfu/g

Cd

≤0.5ppm

Coliforms

Negative

Hg

≤0.1ppm

E.Coli

Negative

Packing

Pack in 25kgs paper-drums, inner by double plastic bag

Shelf life

24 months under the above condition, and in its original package


What are the chemical components of saffron extract??
1. Volatile oils The volatile oil component in the saffron corolla pistil (stigma) is produced by the degradation of carotenes such as zeaxanthin and has a special structure. It is mainly safranal in trimethylcycloethylene derivatives, accounting for 30% of the total volatile oil. 72%, it is the degradation product of crocin, and is also one of the quality control indicators of the traditional Chinese medicine Zangsafflower. Some scholars have identified 46 compounds from saffron volatile oil, accounting for 90.99% of the total volatile oil. Among them, 5 ketone compounds accounted for 6.16%, 5 aldehyde compounds accounted for 2.39%, 6 alcohol compounds accounted for 4.98%, 6 acid compounds accounted for 19.77%, 8 olefin compounds accounted for 36.42%, and olefin oxides 2 compounds accounted for 5.74%, 8 alkane compounds accounted for 12.5%, 2 ester compounds accounted for 0.48%, and 4 other compounds accounted for 2.55%. Among the identified volatile oil components of saffron, the ones with relatively high content are mainly olefins and olefin oxides, which are terpenoid compounds. In addition, the ones with relatively high content are acid compounds. 2. Flavonoids Flavonoids are mainly distributed in the perianth of saffron. Common ones include vetch glycoside, quercetin-3-p-coumaryl Chemicalbook glucoside, and kaempferol-3-glucose-6-acetylglucoside. And kaempferol-3-glucose-glucoside, delphinidin, trimethyldelphinidin, etc. 3. Volatile oil precursors. Some of the volatile oil precursors produced through different degradation pathways during the drying and storage of saffron stigmas are glycoside compounds of trimethylcyclohexene derivatives, mainly including crocin and so on. Crocein is the main bitter component in saffron. It can be converted into safranal under acidic or alkaline conditions or under the action of enzymes. This is also the reason why the content of safranal in different varieties is different. 4. Conjugated polyenes and their glycosides Conjugated polyenes and their glycosides are the main colored components in the traditional Chinese medicine saffron. It mainly includes the following two categories: (1) Carotenoids and their glycosides Crocetin is the main component of carotenoids and their glycosides. Including the carotenoid crocetin and its glycosides, such as gentiobioside, glucoside, digentisic acid glycoside, gentioglucoside and diglucoside; B-crocetin, C-crocetin, etc. (2) Carotenes mainly include A and B-carotene, such as lycopene and zeaxanthin. 5. Others mainly include phenols, chitinase, triterpene saponins and steroidal saponins.
What is the function of saffron extract?
1. Effect on the uterus Saffron extract has an exciting effect on both the isolated uterus and the in vivo uterus of mice, guinea pigs, rabbits, dogs and cats. Pregnant uterus is more sensitive; the order of intensity of various safranin extracts is: decoction > ethanol extract > volatile components > ether extract. The effect of stimulating the uterus can be partially blocked by ergotamine ethanesulfonate and is insensitive to atropine. Therefore, it is believed that part of the effect on the uterus is a direct effect on uterine myocytes, and part is related to adrenergic receptors.
2. Effect on the circulatory system Saffron extract can lower the blood pressure of anesthetized dogs and cats for a long time and has an exciting effect on breathing. When reducing blood pressure, the renal volume decreases, indicating renal vasoconstriction, and also has a constrictive effect on toad blood vessels. It has a significant inhibitory effect on the isolated toad heart. According to chemical analysis, the components that inhibit the heart are related to potassium salts. Therefore, future pharmacological research on saffron should first remove potassium salts.
3. Anti-tumor effect Saffron preparations have obvious anti-tumor and anti-cancer abilities, especially saffron extract (dimethylcrocetin) on leukemia, ovarian cancer, colon cancer, rhabdomyosarcoma, colon cancer, papillosarcoma, and flat cell tumor and soft tissue sarcoma, etc. all have strong inhibitory effects. Its anti-cancer mechanism may be to destroy the DNA synthase system, that is, to destroy the DNA-protein contact mediators such as topoisomerase II that are crucial for cellular DNA synthesis, thereby inhibiting the synthesis of DNA and RNA, thereby inhibiting the growth of tumor cells. . In addition, crocins also inhibit the activity of cellular protein kinases and the expression of proto-oncogenes.
4. Effect on liver and gallbladder Saffron extract has a choleretic effect, and its active ingredients are α-crocetin sodium salt and crocetin ester. α-Saffron acid can lower cholesterol and increase fat metabolism. It can be used with traditional Chinese medicines such as hawthorn, cassia, and Alisma to treat fatty liver.
5. Antioxidant effect Saffron extract, especially crocin, can effectively inhibit the activity of oxygen free radicals and xanthine oxidase, showing antioxidant biological activity.
6. Protect the kidneys. By studying the rat C-BSA nephritis model, it was found that proteinuria and renal pathological damage were reduced in rats in the experimental group. Among them, saffron mainly inhibits cyclooxygenase and reduces the synthesis of prostaglandins, thereby unblocking renal capillaries, increasing blood flow, and promoting the repair of inflammatory damage. It is suggested that saffron can interfere with the occurrence of renal inflammation by improving the release of platelets and inflammatory mediator Chemicalbook.
7. Intervention in arrhythmia Crocemic acid, the active ingredient in saffron extract, has a good effect on ventricular arrhythmia models induced by aconitine, ouabain and calcium chloride, providing experiments for the use of saffron in the treatment of arrhythmia. This provides a feasibility basis for further development and research on saffron as a traditional Chinese medicine preparation against arrhythmia and myocardial ischemia, suggesting that saffron may be called a new type of preventive health-care traditional Chinese medicine for preventing cardiovascular and cerebrovascular diseases.
8. Regulate immune function. Saffron extract has obvious effects of promoting blood circulation and removing blood stasis, antibacterial and anti-inflammatory, and then enhances the body's endurance and increases the content of immune cells, thereby improving the body's immunity, regulating the body's qi and blood movement, and balancing the human body. The role of yin and yang.
9. Prevent and treat atherosclerosis. Saffron extract has good efficacy in regulating blood lipids, lowering blood pressure and thus preventing and treating atherosclerosis.
10. Retinal protection: New Zealand white rabbits were used to create an animal model of high intraocular pressure. A certain dose of saffron extract was injected from the ear vein once a day, and a high pressure control group was established. The results showed that the number of retinal ganglion cells in the treatment group was significantly greater than that in the high-pressure control group (P<0.05), indicating that saffron extract improved retinal blood circulation and blocked the effects of ischemia and hypoxia on retinal ganglion cells under chronic high intraocular pressure conditions ( RGC) damage and protect RGC. It is suggested that saffron extract may protect RGCs by reducing free radicals in the retina and blocking free radical damage to the membrane structure, subcellular organelles and nuclei of RGCs.
11. Other effects Saffron ethanol extract (CSE) can prevent ethanol-induced inhibition of long-term potentiation (LPT) in the hippocampus. In the serrated gyrus of anesthetized mice, CSE (250 mg·kg-1) can also effectively prevent LPT inhibition caused by acetaldehyde without affecting the learning function of mice. The water extract of saffron can significantly inhibit the reproductive toxicity produced by anti-cancer drugs such as cisplatin, cyclophosphamide, mitomycin C and urethan, while the inhibitory effect There was no significant relationship between the size and dose. This is mainly because saffron extract significantly reduces the effects of reproductive toxicity on liver glutathione S-transferase (GST).

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Joyous Health provides Saffron extract powder OEM services. We can customize formulas for customers, private labels, capsules, tablets, soft capsules and sachets, low MOQ, which is suitable for direct sales by brands. Our OEM product shipping channels are stable and delivery times are fast and worthy of customers' trust, we have served more than 300 brands.


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