Nicotinamide Adenine Dinucleotide Phosphate,coenzyme II sodium salt; oxidized coenzyme II (NADP) suppliers and manufacturers,NADP powder

Nicotinamide adenine dinucleotide phosphate (nicotinamide adenine dinucleotide phosphate) abbreviation NADP was once called pyridine triphosphate (TPN) or co-dehydrogenase II or oxidized coenzyme II. It is a coenzyme that combines nicotinamide adenine dinucleotide with a phosphate molecule through an ester bond.

Product Name

Nicotinamide Adenine Dinucleotide Phosphate

Specification

oxidative coenzyme II

CAS No.

24292-60-2

Chemical Formula

C21H26N7Na2O17P3

Appearance

White powder

Other Names

Pyridine triphosphate (TPN)

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Desciption

Product information
What is Nicotinamide Adenine Dinucleotide Phosphate powder?
NADP is a coenzyme called reduced coenzyme II, its scientific name is nicotinamide adenine dinucleotide phosphate, also written as [H]. It plays the role of hydrogen transfer body in many chemical reactions in living organisms, which is of great significance.
NAD+ and NADP+: nicotinamide adenine dinucleotide (NAD+, coenzyme I) and nicotinamide adenine dinucleotide phosphate (NADP+, coenzyme II, the oxidized form of NADPH).
NAD+ and NADP+ mainly serve as coenzymes of dehydrogenase and act as hydrogen transmitters in enzymatic reactions. They are single hydrogen transmitters.
NADPH is usually used as a reducing agent in biosynthesis and cannot directly enter the respiratory chain to accept oxidation. Only under the action of special enzymes, the H on NADPH is transferred to NAD+, and then NAD+ enters the respiratory chain.
NADPH is reduced during the photolysis of water in the light reaction stage of photosynthesis, and then acts as a reducing agent in the dark reaction. NADP+ and ADP are reduced to NADPH and ATP in the light reaction, and then enter the dark reaction (Calvin cycle) , are oxidized to ADP and NADP+ in the dark reaction, and then re-enter the light reaction to form a cycle. See photosynthesis for details.
Nicotinamide adenine dinucleotide phosphate, also known as NADP⁺, differs from NAD⁺ only in that its molecule has an extra phosphate group. Nicotinamide adenine dinucleotide phosphate is also a transhydrogen coenzyme; however, it is also involved in anabolic processes by carrying the necessary hydrogen in reduction reactions. It is present in all biological cells. It is mainly found in foods of animal origin and in relatively small amounts in foods of plant origin.
Joyous Turkestrone powder specification

Terms	Standard	Terms	Standard
Product Name	Nicotinamide Adenine Dinucleotide Phosphate	Appearance	White powder
Assay	98%	Loss on Drying	≤2%
Total Heavy Metals	≤10 ppm	Ash	≤2%
As	≤0.5ppm	Total Plate Count	≤750 cfu/g
Pb	≤0.5ppm	Yeast and Mold	≤100 cfu/g
Cd	≤0.5ppm	Coliforms	Negative
Hg	≤0.1ppm	E.Coli	Negative
Packing	Pack in 25kgs paper-drums, inner by double plastic bag	Shelf life	24 months under the above condition, and in its original package

What are the similarities and differences in the functions of NAD and NADP?
Reduced coenzyme 1 and reductive coenzyme 2 are both synthesized through the protein synthesis process in cells.
NAD+ and NADP+: nicotinamide adenine dinucleotide (NAD+, coenzyme I) and nicotinamide adenine dinucleotide phosphate (NADP+, coenzyme II, the oxidized form of NADPH).
1. The reaction of reducing coenzyme 1:
1.ADP ribosyltransferase or polyribosyl polymerase (PARP):
Such enzymes are involved in DNA repair, gene expression, cell cycle progression, cell survival, chromosome reconstruction, and gene stability;
2. Cyclic ADP ribose synthase (cADPR synthases) Cyclic ribose polymerase (cADP synthase):
It is composed of a pair of extracellular enzymes, called lymphocyte antigens CD38 and CD157, which use NAD as a substrate to generate cyclic ADP ribose (an important calcium signaling messenger), which plays a role in maintaining calcium homeostasis and immune response. has important physiological significance;
3. III protein lysine deacetylase Sirtuins:
They are a type of histone deacetylase, with 7 different subtypes (SIRT1-SIRT7), which play an important role in cellular stress resistance, energy metabolism, apoptosis and aging. A large number of studies have shown that Sirtuins' regulation of metabolic balance will directly affect various metabolism-related diseases. For example, SIRT1 regulates the acetylation status of histones with the participation of coenzyme I (NAD), which is beneficial to enhancing the heart's tolerance to oxidative stress. , plays an important role in regulating myocardial energy metabolism and anti-aging.
It participates in thousands of physiological reactions, such as the cellular tricarboxylic acid cycle (TCA), fat beta oxidation, etc., and is of great significance in the metabolic utilization of nutrients such as sugar, fat, and amino acids. It is also the only substrate for coenzyme I consuming enzymes such as NAD+-dependent ADP ribosyltransferase. This type of enzyme decomposes coenzyme I (NAD+) as a substrate into ADP ribose and nicotinamide (Nam), and plays different physiological functions in different cells, such as participating in DNA repair, regulating cellular oxidative stress and other physiological functions.
2. The reaction of reducing coenzyme 2:
1. NAD+ and NADP+: nicotinamide adenine dinucleotide (NAD+, coenzyme I) and nicotinamide adenine dinucleotide phosphate (NADP+, coenzyme II, the oxidized form of NADPH).
2. NAD+ and NADP+ mainly serve as coenzymes of dehydrogenase and act as hydrogen transmitters in enzymatic reactions. They are single hydrogen transmitters.
3. NADPH is usually used as a reducing agent in biosynthesis and cannot directly enter the respiratory chain to accept oxidation. Only under the action of special enzymes, the H on NADPH is transferred to NAD+, and then NAD+ enters the respiratory chain.

4. NADPH is reduced during the photolysis of water in the light reaction stage of photosynthesis, and then acts as a reducing agent in the dark reaction. NADP+ and ADP are reduced to NADPH and ATP in the light reaction, and then enter the dark reaction (Calvin cycle), are oxidized to ADP and NADP+ in the dark reaction, and then re-enter the light reaction to form a cycle. See photosynthesis for details.

Package and delivery

Delivery
1-80kg	80-300kg	More than 300kg
More suitable for express transportation, door-to-door	More suitable for air transportation,airport-to-airport	More suitable for ocean transportation,port-to-port
7-10 days for delivery time	3-4 days for delivery time	20-40 days for delivery time

What service we can provide
Joyous Health provides Nicotinamide Adenine Dinucleotide Phosphate powder OEM services. We can customize formulas for customers, private labels, capsules, tablets, soft capsules and sachets, low MOQ, which is suitable for direct sales by brands. Our OEM product shipping channels are stable and delivery times are fast and worthy of customers' trust, we have served more than 300 brands.

Joyous Health Factory information and certifications
Xi'an Joyous Health Biotechnology Co., Ltd. was established in 2011. Over the past 12 years, Joyous Health has obtained ISO 9001, FDA, ISO 22000, and GMP certifications.
Joyous Health has an advanced laboratory to control quality, so that each batch of products undergoes strict testing, and has professional R&D personnel to provide customized product services.
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Where to buy Nicotinamide Adenine Dinucleotide Phosphate powder?
We offer the best Nicotinamide Adenine Dinucleotide Phosphate powder at the most competitive price. Nicotinamide Adenine Dinucleotide Phosphate Powder bulk and wholesale powder have been 3rd lab-tested and verified for both product purity and identity.
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