Baicalin powder

Baicalin (baicalin) is a flavonoid extracted and isolated from the dried roots of the dicotyledonous Lamiaceae plant Scutellaria baicalensis Georgi. Baicalin is a commonly used traditional Chinese medicine. In the field of anti-tumor, baicalin It also has good effects

Product Name

Baicalin

Appearance

Yellow powder

Specification

85%

CAS No

21967-41-9

Molecular

C21H18O11

Package

25kg cardboard drum

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Desciption

Product information
What is Baicalin Powder?
Baicalin is a flavonoid extracted and isolated from the dried roots of the dicotyledonous Lamiaceae plant Scutellaria baicalensis Georgi. It is a light yellow powder at room temperature and has a bitter taste. Insoluble in methanol, ethanol, acetone, slightly soluble in chloroform and nitrobenzene, almost insoluble in water, soluble in hot acetic acid. It appears green when exposed to ferric chloride, and produces an orange precipitate when exposed to lead acetate. Soluble in alkali and ammonia, it appears yellow at first and soon turns to dark brown. It has significant biological activity, including antibacterial, diuretic, anti-inflammatory, cholesterol-lowering, anti-thrombosis, asthma relief, purging fire and detoxification, hemostasis, anti-tocolysis, anti-allergic and antispasmodic effects. It is also a source of mammalian liver salivary enzymes. Specific inhibitors have the effect of regulating certain diseases and also have strong anti-cancer physiological effects.
Joyous Baicalin powder specification

Terms	Standard	Terms	Standard
Product Name	Baicalin	Appearance	Yellow Powder
Purity	85%	Loss on Drying	≤8%
Total Heavy Metals	≤10 ppm	Ash	≤1%
As	≤0.5ppm	Total Plate Count	≤1000 cfu/g
Pb	≤0.5ppm	Yeast and Mold	≤100 cfu/g
Cd	≤0.5ppm	Coliforms	Negative
Hg	≤0.1ppm	E.Coli	Negative
Packing	Pack in 25kgs paper-drums, inner by double plastic bag	Shelf life	24 months under the above condition, and in its original package

What is the role of Baicalin?
1. Anti-tumor effect: In vitro, baicalin has a significant inhibitory effect on the proliferation of S180 and Hep-A-22 tumor cells. As the drug concentration increases, the inhibitory effect gradually increases, and the survival rate of Hep-A-22 mice is significantly prolonged. Number of survival days.
2. Anti-pathogen effect: Baicalin has a wide antibacterial range and has a strong effect on Staphylococcus aureus and Pseudomonas aeruginosa. Sun Dongmei and others have conducted antibacterial tests on drug-resistant Staphylococcus aureus in vitro and on drug-resistant Staphylococcus aureus in vivo. Protective effect of Staphylococcus aureus infected mice and observe the antibacterial effect of baicalin. The minimum inhibitory concentrations of baicalin and compound sulfamethoxazole (SMZ-TMP) against drug-resistant Staphylococcus aureus are 2 mg/ml and 0.45 mg/ml respectively. In vivo experiments show that baicalin (100 mg/kg) can reduce The mortality rate of mice infected with drug-resistant Staphylococcus aureus indicates that baicalin has an antibacterial effect on drug-resistant Staphylococcus aureus.
3. Protective effect on liver injury: Use CCl4 and D-galactose to make a mouse acute liver injury model, and use colorimetric analysis to measure the activities of mouse serum aspartate aminotransferase and alanine aminotransferase; measure mouse serum Superoxide dismutase, glutathione peroxidase activity and malondialdehyde content. Results Baicalin could significantly reduce the increase in serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in mice with acute liver injury caused by CCl4 and D-galactose; it also inhibited serum superoxidation in mice with acute liver injury. The activities of substance dismutase (SOD) and glutathione peroxidase (GSH-Px) are significantly increased, and the content of malondialdehyde (MDA) is reduced. The results showed that baicalin had a protective effect on acute liver injury in mice induced by CCl4 and D-galactose. In the experiment, SOD and GSH-Px in the administration group were significantly higher than those in the model group, while MDA content was significantly lower, indicating that the hepatoprotective mechanism of baicalin is closely related to its resistance to free radical lipid peroxidation.
4. Improvement of diabetic nephropathy: Diabetic nephropathy (DN) is one of the most common microvascular complications of diabetes mellitus (DM), and research on its pathogenesis has always been a hot topic in the field of diabetes at home and abroad. Hyperglycemia is the initiating factor that causes diabetic nephropathy, and through a series of processes in the body, it can cause oxidative stress and inflammatory reactions inside the body, leading to the activation of the local cytokine network in the kidney and leading to DN. During the entire process, the renin-angiotensin system plays an important role, among which angiotensin II (Ang II) is the most active factor in this system and is most closely related to DN. After baicalin treatment, AngII was significantly restored, which is the target of baicalin's protection of renal function in DN rats. That is, baicalin treats or protects DN by reducing the activity of the renin-angiotensin system (RAS) under hyperglycemia. Renal function in rats. In addition, baicalin can also restore kidney function by reducing blood pressure and intraglomerular pressure, improving blood internal environment and circulatory function after reducing AngII.
5. Repair and protective effect on brain injury: Hu Xiumei used the suture method to establish a model of focal cerebral ischemia-reperfusion injury caused by middle cerebral artery occlusion in rats, and observed the effects of baicalin on behavioral scores and cerebral infarction in rats with cerebral ischemia-reperfusion. rate, brain water content, and the effects of brain tissue NO, NOS, MDA, and SOD. It was found that baicalin can significantly improve the behavioral disorders caused by cerebral ischemia-reperfusion in rats, reduce the infarction rate, reduce the water content of brain tissue, and significantly reduce the content of NO and the activity of NOS in the brain tissue, thereby reducing the neurological effects of NO. Cytotoxicity. At the same time, baicalin can reduce the content of MDA in the brain tissue of ischemia-reperfusion rats and increase the activity of SOD, thereby inhibiting lipid peroxidation caused by free radicals and reducing the damage of free radicals to brain tissue. Baicalin has a significant protective effect on cerebral ischemia-reperfusion injury in rats, which may be related to its antioxidant effect in the early stage of cerebral ischemia-reperfusion. At the same time, baicalin has protective and repairing effects on learning and memory function impairment in cerebral ischemia-reperfusion model mice.
6. Impact on retinopathy: Song Haogang et al. established an animal model of inflammatory retinal edema, used optical coherence tomography (OCT) to continuously observe changes in the thickness of inflammatory retinal edema, and compared it with the results of retinal morphology observation and retinal thickness measurement. In comparison, the effect of baicalin in inhibiting retinal inflammatory edema was quantified from imaging and histology, and the effects of different concentrations of the drug were evaluated. Baicalin has a significant inhibitory effect on retinal extracellular inflammatory edema and is no less effective than topical corticosteroids.
7. Anti-allergic reaction: The reaction structure of baicalin is the same as that of the desensitizing drug cromoglycate disodium, so the anti-allergic effect is also similar.
Package and delivery

Delivery
1-80kg	80-300kg	More than 300kg
More suitable for express transportation, door-to-door	More suitable for air transportation,airport-to-airport	More suitable for ocean transportation,port-to-port
7-10 days for delivery time	3-4 days for delivery time	20-40 days for delivery time

What service we can provide
Joyous Health provides Baicalin powder OEM services. We can customize formulas for customers, private labels, capsules, tablets, soft capsules, sachets, and pellets with low MOQ, which is suitable for direct sales by brands. Our OEM product shipping channels are stable and delivery times are fast and worthy of customers' trust, we have served more than 300 brands.

Joyous Health Factory information and certifications
Xi'an Joyous Health Biotechnology Co., Ltd. was established in 2011. Over the past 12 years, Joyous Health has obtained ISO 9001, FDA, ISO 22000, and GMP certifications.
Joyous Health has an advanced laboratory to control quality, so that each batch of products undergoes strict testing, and has professional R&D personnel to provide customized product services.
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Where to buy Baicalin powder?
We offer the best Baicalin powder at the most competitive price. Baicalin Powder bulk and wholesale powder have been 3rd lab-tested and verified for both product purity and identity.
We also provide Baicalin powder in bulk order or wholesale according to client needs. Just submit the requirements in the bottom form, and we will reply soon!

Contacts: Faith Feng
Email:[email protected]
Tel and Whatsapp:+86 17391747738

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Contact: Xi'an international enterprise center B building, Fengcheng 4 road, Xi'an City, Shaanxi province, China; [email protected]; +86 17391747738

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