• Bacopa monnieri extract
  • Bacopa monnieri extract

Bacopa monnieri extract

Bacopa monnieri extract is extracted and processed from the whole Bacopa monnieri plant of the Scrophulariaceae family, Bacopa monnieri, and mainly contains triterpene saponin compounds. It has pharmacological activities such as memory improvement, sedation, anti-epileptic, anti-inflammatory, antipyretic and analgesic.
Product Name
Bacopa monnieri extract
Appearance
Brown powder
Specification
20%-50%
Botanical Name
Bacopa monnieri (L.) Wettst.
Main ingredients
Saponins
Package
25kg cardboard drum
  • Bacopa monnieri extract

Desciption

Product information                                                                                                                                                  
What is Bacopa monnieri extract powder?
Bacopa monnieri extract is extracted and processed from the whole Bacopa monnieri plant of the Scrophulariaceae family, Bacopa monnieri, and mainly contains triterpene saponin compounds. The whole Bacopa monnieri plant contains BacogeninA, nicotine and betulinic acid. In addition, two flavonoid glycosides were isolated, namely ChemicalbookGlucuronyl-7-apigenin and Glucuronyl-7-luteolin.
Joyous Bacopa monnieri extract powder specification
Terms Standard Terms Standard
Product Name Bacopa monnieri extract

Appearance

Brown powder

Assay 20%-50%

Loss on Drying

≤2%

Total Heavy Metals

≤10 ppm

Ash

≤2%

As

≤0.5ppm

Total Plate Count

≤750 cfu/g

Pb

≤0.5ppm

Yeast and Mold

≤100 cfu/g

Cd

≤0.5ppm

Coliforms

Negative

Hg

≤0.1ppm

E.Coli

Negative

Packing

Pack in 25kgs paper-drums, inner by double plastic bag

Shelf life

24 months under the above condition, and in its original package


How about Bacopa monnieri extract?
Bacopa monnieri extract is clinically used in traditional Chinese medicine to treat dysentery, red and swollen eyes, erysipelas, hemorrhoids and elephantiasis for external use. Bacopa monnieri extract is also widely used in the supplement field.
Bacopa monnieri supplementation has many functions for the human body:
1. Pharmacological activity on nerves
(1) Beneficial effects on learning and memory Research shows that Bacopa monnieri and its extracts have brain-building effects. Bacopa monnieri and its ethanol extract can significantly improve the learning ability of rats. The effect of promoting cognitive function is mainly due to the two active saponins of Bacopa monnieri saponin A and B in the ethanol extract. In addition to promoting the learning and memory functions of normal rats, the active ingredients can also inhibit amnesia (memory loss) caused by scopolamine, electroshock and restraint stress.
(2) Anti-anxiety effect Bacopa monnieri extract is different from benzodiazepine anti-anxiety drugs. The former can improve cognitive function while producing anti-anxiety effects, while the latter has the side effect of causing dementia. A rat anti-anxiety experimental model (elevated plus maze model) was used to conduct a comparative study on the anti-anxiety effects of BM standard extract and benzodiazepines. Rats were orally administered 5, 10 and 20 mg/kg BM extract and intraperitoneally injected Lorazepam (LZP) 0.5mg/kg. Compared with lorazepam, high-dose Bacopa monnieri extract has a stronger anti-anxiety effect and is significantly better than LZP. Bacopa monnieri not only does not cause dementia, On the contrary, it can enhance the memory function of demented animals and people.
(3) Antidepressant effect: The methanol standard extract of Bacopa monnieri has a strong antidepressant effect on rodent depression models. Compared with the antidepressant imipramine (15mg/kg), it has better effects on forced swimming and acquired helpless depression. In the model, 20 or 40 mg/kg of Bacopa monnieri was given once a day for 5 days, which can produce obvious antidepressant effects.
(4) The anticonvulsant effect of Bacopa monnieri was used alone or in combination with phenytoin (an anticonvulsant drug that causes cognitive dysfunction), and was evaluated using the mouse passive avoidance test, the maximum number of electroshock epileptic seizures, and motor function. The results show that , Phenytoin can damage cognitive function, while Bacopa monnieri can reverse the damage of phenytoin on cognitive function, significantly improve memory acquisition and memory retention Chemicalbook, but does not affect the anticonvulsant effect of phenytoin; Bacopa monnieri can be used alone or in combination with other The combined use of anti-epileptic drugs has also confirmed that Bacopa monnieri has a strong anti-epileptic effect and can correct the damage to cognitive function caused by anti-epileptic drugs.
2. Anti-tumor effect: Bacopa monnieri extract can inhibit the growth of tumor cells at low concentrations; the toxicity at high concentrations still needs further in vivo experiments to clarify. The drug may work by inhibiting DNA replication.
3. Liver protection studies have shown that Bacopa monnieri prevents the inhibition of antioxidant enzymes and the reduction of glutathione levels, and inhibits the increase in peroxidized lipids after morphine administration, thereby producing liver protection against morphine-induced liver poisoning in rats. effect.
4. Relax smooth muscle Bacopa monnieri ethanol extract has a relaxing effect on all isolated tissues such as rabbit and guinea pig isolated trachea, pulmonary artery and aorta, and can reduce the contraction of guinea pig tracheal strips caused by histamine in a dose-dependent manner. Among them, the most obvious effect was on guinea pigs, but the tracheal specimens were completely relaxed. The relaxing effect of the extract on blood vessels could not be blocked by atropine and pracerolol, but the relaxing effect of the extract on tracheal specimens could be partially blocked by pracerolol. Indomethacin can block the tissue relaxation caused by plant extracts, and the plant extracts have the same relaxing effect on blood vessels with or without endothelium. The results suggest that the relaxation caused by Bacopa may involve prostacyclin compounds and β-adrenergic receptors. In addition, this relaxation does not depend on the activation of endothelial and muscarinic receptors.
5. Other effects In addition to the psychoactive effects, the anti-inflammatory, cardiac and other pharmacological effects of Bacopa monnieri preparations or extracts were also evaluated. The inhibitory effect of Bacopa monnieri on experimental inflammation was compared with the anti-inflammatory drug indomethacin. The results showed that BM effectively inhibited the experimental inflammatory response by inhibiting prostaglandin synthesis and partially stabilizing the lysosomal membrane. And at anti-inflammatory doses, Bacopa does not cause gastrointestinal irritation. Bacopa monnieri extract can heal different types of inflammation.
Package and delivery                                                                                                                                                

Delivery
1-80kg 80-300kg More than 300kg
More suitable for express transportation, door-to-door More suitable for air transportation,airport-to-airport More suitable for ocean transportation,port-to-port
7-10 days for delivery time 3-4 days for delivery time 20-40 days for delivery time

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Joyous Health provides Bacopa monnieri extract powder OEM services. We can customize formulas for customers, private labels, capsules, tablets, soft capsules and sachets, low MOQ, which is suitable for direct sales by brands. Our OEM product shipping channels are stable and delivery times are fast and worthy of customers' trust, we have served more than 300 brands.


Joyous Health Factory information and certifications                                                                                            
Xi'an Joyous Health Biotechnology Co., Ltd. was established in 2011. Over the past 12 years, Joyous Health has obtained ISO 9001, FDA, ISO 22000, and GMP certifications.
Joyous Health has an advanced laboratory to control quality, so that each batch of products undergoes strict testing, and has professional R&D personnel to provide customized product services.
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